ROLE OF CT AND MRI IN EVALUATION OF INTRACRANIAL ANEURYSM: A HOSPITAL-BASED PROSPECTIVE CROSS-SECTIONAL DIAGNOSTIC STUDY

Autori

  • Dr. Amit Kumar Gupta Junior Resident III, Department of Radiodiagnosis, Katihar Medical College and Hospital, Katihar
  • Dr. Md Shahzeb Alam Junior Resident II, Department of Radiodiagnosis, Katihar Medical College and Hospital, Katihar
  • Dr. Manish Jaiswal Associate Professor, Department of Radiodiagnosis, Katihar Medical College and Hospital, Katihar

DOI:

https://doi.org/10.51168/qv6jj571

Cuvinte cheie:

Intracranial aneurysm, CT angiography, MR angiography, digital subtraction angiography,, subarachnoid haemorrhage, saccular aneurysm, diagnostic accuracy

Rezumat

Introduction: To compare the diagnostic performance of computed tomography (CT) and magnetic resonance imaging (MRI), individually and in combination, in detecting, characterising and evaluating intracranial aneurysms.

Materials and Methods: This hospital-based prospective cross-sectional study was carried out in the Department of Radiodiagnosis, Katihar Medical College and Hospital, Katihar, over two and a half years. Fifty consecutive patients with suspected or known intracranial aneurysm underwent CT angiography (16-slice multidetector scanner) and MR angiography (1.5 Tesla), with digital subtraction angiography (DSA) as the reference standard. Data were analysed in SPSS using descriptive statistics, the chi-square test and yield analysis.

Results: The mean age was 43.42 ± 11.64 years, 58% of patients were male and 60% were from semi-urban areas. Cranial nerve palsy (36%) was the commonest presentation, followed by subarachnoid haemorrhage (30%). CT detected aneurysms in 40 of 50 patients (sensitivity 80%) and MRI in 47 of 50 (sensitivity 94%); DSA confirmed aneurysms in all 50. The middle cerebral artery (34%) and anterior communicating artery (22%) were the commonest sites. Saccular and fusiform aneurysms each accounted for 36% of cases, and 52% had ruptured at presentation. Detection by either modality was not significantly associated with aneurysm size or morphology, and rupture was not significantly associated with risk factors (all p > 0.05).

Conclusion: MRI showed higher sensitivity and diagnostic accuracy than CT, particularly for small lesions, while CT remained valuable for rapid assessment in emergencies. A combined approach gives the most comprehensive evaluation.

Recommendation: CT angiography is suggested as the first-line investigation in acute presentations, with MR angiography added in stable patients, when CT is negative or equivocal, and for detailed characterisation. Larger multicentre studies that include aneurysm-negative patients are needed.

Biografii autori

  • Dr. Amit Kumar Gupta, Junior Resident III, Department of Radiodiagnosis, Katihar Medical College and Hospital, Katihar

    is a Junior Resident (Year III) in the Department of Radiodiagnosis, Katihar Medical College and Hospital, Katihar.

  • Dr. Md Shahzeb Alam, Junior Resident II, Department of Radiodiagnosis, Katihar Medical College and Hospital, Katihar

    is a Junior Resident (Year II) in the Department of Radiodiagnosis, Katihar Medical College and Hospital, Katihar, and is the corresponding author.

  • Dr. Manish Jaiswal, Associate Professor, Department of Radiodiagnosis, Katihar Medical College and Hospital, Katihar

    is an Associate Professor in the Department of Radiodiagnosis, Katihar Medical College and Hospital, Katihar.

Referințe

1. National Institute of Neurological Disorders and Stroke. Cerebral aneurysms [Internet]. Available from: https://www.ninds.nih.gov/health-information/disorders/cerebral-aneurysms

2. Cardiovascular and Interventional Radiological Society of Europe (CIRSE). Intracranial aneurysm [Internet]. Available from: https://www.cirse.org/patients/general-information/medical-conditions/intracranial-aneurysm/

3. Intracranial aneurysm - basic information and clinical research. European Clinical Trials Information Network [Internet]. Available from: https://clinicaltrials.eu/disease/intracranial-aneurysm/

4. The pathophysiology of aneurysms. Oxford Textbook of Neurological Surgery [Internet]. Available from: https://academic.oup.com/book/35442/

5. Han Y, Qin H, Cui J, Zeng X, Zhao B, Han Y, et al. A modified mouse model of intracranial aneurysm based on hemodynamic change and hypertension. J Vis Exp. 2025;(216). https://doi.org/10.3791/68087

6. Kim B. Unruptured intracranial aneurysm: screening, prevalence and risk factors. Neurointervention. 2021;16(3):201-3.

https://doi.org/10.5469/neuroint.2021.00451

7. Prevalence of intracranial aneurysms with emphasis on ethnicity and race. American Journal of Neuroradiology [Internet]. Available from: https://www.ajnr.org/content/early/2023/04/27/ajnr.A7869

8. Madhugiri V, Ambekar S, Pandey P, Yavagal D. Cerebral aneurysm treatment in India: results of a national survey regarding practice patterns in India. Neurol India. 2016;64:62-9. https://doi.org/10.4103/0028-3886.178044

9. Cerebral aneurysm - symptoms, diagnosis and treatment. BMJ Best Practice [Internet]. Available from: https://bestpractice.bmj.com/topics/en-gb/490

10. Hackett AM, Koester SW, Rhodenhiser EG, Scherschinski L, Rulney JD, Naik A, et al. A comprehensive assessment of self-reported symptoms among patients harboring an unruptured intracranial aneurysm. Front Surg. 2023;10:1148274. https://doi.org/10.3389/fsurg.2023.1148274

11. Gkasdaris G, Dumot C, Nerntengian N, Birbilis T. Editorial: Non-specific symptoms of unruptured intracranial aneurysms - new concepts in pathophysiology, hemodynamics and potential warning signs. Front Surg. 2025;12. https://doi.org/10.3389/fsurg.2025.1572304

12. Stanford Health Care. Risk factors - brain aneurysm [Internet]. Available from: https://stanfordhealthcare.org/medical-conditions/brain-and-nerves/brain-aneurysm/risk-factors.html

13. Cebral JR, Raschi M. Suggested connections between risk factors of intracranial aneurysms: a review. Ann Biomed Eng. 2013;41(7):1366-83.

https://doi.org/10.1007/s10439-012-0723-0

14. Backes D, Rinkel GJE, Laban KG, Algra A, Vergouwen MDI. Patient- and aneurysm-specific risk factors for intracranial aneurysm growth. Stroke. 2016;47(4):951-7. https://doi.org/10.1161/STROKEAHA.115.012162

15. Allaw S, Khabaz K, Given TC, Montas D, Alcazar-Felix RJ, Srinath A, et al. A review of intracranial aneurysm imaging modalities, from CT to state-of-the-art MR. AJNR Am J Neuroradiol. 2025;46(6):1082-92. https://doi.org/10.3174/ajnr.A8549

16. Zhou Y, Weng W. Research progress in medical imaging for intracranial aneurysms: technological advances in diagnosis, management, and clinical integration. Front Neurol. 2025;16:1657536. https://doi.org/10.3389/fneur.2025.1657536

17. Imaging of intracranial aneurysms. RADIOBITE [Internet]. 2025. Available from: https://radiobite.com/imaging-of-intracranial-aneurysms/

18. Digital subtraction angiogram: beginner's perspective [Internet]. Available from: https://www.researchgate.net/publication/382060618

19. Matsukawa S, Ishii A, Fushimi Y, Grinstead J, Ahn S, Kikuchi T, et al. Efficacy of high-resolution vessel wall MRI in the postoperative assessment of intracranial aneurysms following flow diversion treatment. J Neurosurg. 2024;142:1-10. https://doi.org/10.3171/2024.5.JNS24174

20. Quan T, Ren Y, Li J, Fu X, Jin Y, Ran Y, et al. Enhanced vessel wall magnetic resonance imaging in the follow-up of intracranial aneurysms treated with flow diversion. Eur Radiol. 2024;34(2):833-41. https://doi.org/10.1007/s00330-023-10094-4

21. Lim JH, Yoon DY, Kim ES, Jeon HJ, Lee JY, Seo YL, et al. CT angiography, MR angiography, and their combined use for detection of unruptured intracranial aneurysms: comparison with digital subtraction angiography and 3-dimensional rotational angiography. Clin Neuroradiol. 2025;35(2):355-62.

https://doi.org/10.1007/s00062-024-01491-3

22. Gupta AK. CT angiography versus MR angiography in the evaluation of intracranial aneurysms: a comparative study. 2019;8(1).

23. Mkhize NN, Mngomezulu V, Buthelezi TE. Accuracy of CT angiography for detecting ruptured intracranial aneurysms. SA J Radiol. 2023;27(1):2636.

https://doi.org/10.4102/sajr.v27i1.2636

24. Josephson CB, White PM, Krishan A, Al-Shahi Salman R. Computed tomography angiography or magnetic resonance angiography for detection of intracranial vascular malformations in patients with intracerebral haemorrhage. Cochrane Database Syst Rev. 2014;2014(9):CD009372.

https://doi.org/10.1002/14651858.CD009372.pub2

25. Kapoor K, Kak VK. Incidence of intracranial aneurysms in north-west Indian population. Neurol India. 2003;51(1):22-6.

26. Zhang B, Liu Z, Xu J, Cai J, Ba H, Lin Q, et al. Comprehensive analysis of risk factors for intracranial aneurysm rupture: a retrospective cohort study. Front Neurol. 2025;16:1559484. https://doi.org/10.3389/fneur.2025.1559484

27. Brinjikji W, Zhu YQ, Lanzino G, Cloft HJ, Murad MH, Wang Z, et al. Risk factors for growth of intracranial aneurysms: a systematic review and meta-analysis. AJNR Am J Neuroradiol. 2016;37(4):615-20

Descărcări

Publicat

2026-09-30

Număr

Secțiune

Section of Radiology and Radiotherapy

Cum cităm

Dr. Amit Kumar Gupta, Dr. Md Shahzeb Alam, & Dr. Manish Jaiswal. (2026). ROLE OF CT AND MRI IN EVALUATION OF INTRACRANIAL ANEURYSM: A HOSPITAL-BASED PROSPECTIVE CROSS-SECTIONAL DIAGNOSTIC STUDY. Student’s Journal of Health Research Africa, 7(3), 10. https://doi.org/10.51168/qv6jj571

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