Clinicodemographic Profile and Management Outcomes of Patients with Gallstone Disease: A Cross-Sectional Observational Study.
DOI:
https://doi.org/10.51168/mhdwba36Keywords:
Gallstone disease, Cholelithiasis, Cholecystectomy, Laparoscopy, Ultrasonography, CholedocholithiasisAbstract
Background:
Gallstone disease is a frequent hepatobiliary disorder with wide variation in demographic distribution, clinical presentation, and treatment pathways. Local clinical data are useful for understanding presentation patterns and perioperative outcomes in secondary and tertiary care settings.
Objectives:
To evaluate the clinicodemographic profile, ultrasonographic features, management pattern, and treatment outcomes among patients with gallstone disease.
Methods:
This hospital-based cross-sectional observational study included 50 consecutive adult patients with ultrasonography-confirmed gallstone disease. Demographic details, symptoms, ultrasonographic findings, diagnosis, treatment modality, postoperative complications, and follow-up symptom status were analysed descriptively.
Results:
The mean age was 43.8 +/- 12.6 years, and most patients were aged 31-50 years. Females constituted 68% of cases. Right upper abdominal pain was the commonest symptom, followed by nausea or vomiting and dyspepsia. Ultrasonography showed multiple gallstones in 64%, solitary stones in 36%, gallbladder wall thickening in 30%, pericholecystic fluid in 12%, and common bile duct dilatation in 8% of patients. Laparoscopic cholecystectomy was performed in 80%, open cholecystectomy in 12%, and ERCP followed by cholecystectomy in 8%. Uneventful recovery was noted in 84%, with complete symptom relief in 88%.
Conclusion:
Gallstone disease predominantly affected middle-aged females and commonly presented with right upper abdominal pain. Laparoscopic cholecystectomy was the principal management modality and showed favourable recovery with low complication rates.
Recommendations:
Early ultrasonographic evaluation, risk stratification for common bile duct stones, and timely laparoscopic intervention should be strengthened in routine surgical practice.
References
1. Stinton LM, Shaffer EA. Epidemiology of gallbladder disease: cholelithiasis and cancer. Gut Liver. 2012;6(2):172-187. doi:10.5009/gnl.2012.6.2.172.
2. Lammert F, Gurusamy K, Ko CW, Miquel JF, Mendez-Sanchez N, Portincasa P, et al. Gallstones. Nat Rev Dis Primers. 2016;2:16024. doi:10.1038/nrdp.2016.24.
3. Portincasa P, Moschetta A, Palasciano G. Cholesterol gallstone disease. Lancet. 2006;368(9531):230-239. doi:10.1016/S0140-6736(06)69044-2.
4. Shaffer EA. Epidemiology and risk factors for gallstone disease: has the paradigm changed in the 21st century? Curr Gastroenterol Rep. 2005;7(2):132-140. doi:10.1007/s11894-005-0051-8.
5. Everhart JE, Khare M, Hill M, Maurer KR. Prevalence and ethnic differences in gallbladder disease in the United States. Gastroenterology. 1999;117(3):632-639. doi:10.1016/S0016-5085(99)70456-7.
6. Singh V, Trikha B, Nain CK, Singh K, Bose SM. Epidemiology of gallstone disease in Chandigarh: a community-based study. J Gastroenterol Hepatol. 2001;16(5):560-563. doi:10.1046/j.1440-1746.2001.02484.x.
7. Unisa S, Jagannath P, Dhir V, Khandelwal C, Sarangi L, Roy TK. Population-based study to estimate prevalence and determine risk factors of gallbladder diseases in the rural Gangetic basin of North India. HPB (Oxford). 2011;13(2):117-125. doi:10.1111/j.1477-2574.2010.00255.x.
8. Tazuma S. Gallstone disease: epidemiology, pathogenesis, and classification of biliary stones. Best Pract Res Clin Gastroenterol. 2006;20(6):1075-1083. doi:10.1016/j.bpg.2006.05.009.
9. Friedman GD. Natural history of asymptomatic and symptomatic gallstones. Am J Surg. 1993;165(4):399-404. doi:10.1016/S0002-9610(05)80930-4.
10. Pisano M, Allievi N, Gurusamy K, Borzellino G, Cimbanassi S, Boerna D, et al. 2020 World Society of Emergency Surgery updated guidelines for the diagnosis and treatment of acute calculus cholecystitis. World J Emerg Surg. 2020;15(1):61. doi:10.1186/s13017-020-00336-x.
11. Yokoe M, Hata J, Takada T, Strasberg SM, Asbun HJ, Wakabayashi G, et al. Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis. J Hepatobiliary Pancreat Sci. 2018;25(1):41-54. doi:10.1002/jhbp.515.
12. Okamoto K, Suzuki K, Takada T, Strasberg SM, Asbun HJ, Endo I, et al. Tokyo Guidelines 2018: flowchart for the management of acute cholecystitis. J Hepatobiliary Pancreat Sci. 2018;25(1):55-72. doi:10.1002/jhbp.516.
13. Keus F, de Jong JAF, Gooszen HG, van Laarhoven CJHM. Laparoscopic versus open cholecystectomy for patients with symptomatic cholecystolithiasis. Cochrane Database Syst Rev. 2006;(4): CD006231. doi:10.1002/14651858.CD006231.
14. Buxbaum JL, Abbas Fehmi SM, Sultan S, Fishman DS, Qumseya BJ, Cortessis VK, et al. ASGE guideline on the role of endoscopy in the evaluation and management of choledocholithiasis. Gastrointest Endosc. 2019;89(6):1075-1105.e15. doi:10.1016/j.gie.2018.10.001.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Dr. Banothu Prudhvi Raj, Dr. Banothu Ramakrishna

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.














